Article
Antiplatelet therapy guided by CYP2C19 point-of-care pharmacogenetics plus multidimensional treatment decisions.
Pharmacogenomics - 1 Jan 2024
Voicu Victor, Diehm Nicolas, Moarof Igal, Parejo Sarah, Badiqué Florent, Burden Andrea, Niedrig David, Béchir Markus, Russmann Stefan
Abstract excerpt
Aim: Implementation of CYP2C19 point-of-care (POC) pharmacogenetic (PGx) testing with personalized treatment recommendations. Methods: POC CYP2C19 genotyping plus expert evaluation of risk factors for ischemic and bleeding events. Results: 167 patients underwent PGx testing, 54 (32.3%) were CYP2C19 loss of function carriers, and POC versus standard PGx analysis results for *2 and *3 variants matched in 100%....
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