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Evolutionary dynamics of HIV-1 subtype C in Brazil.

Scientific reports - 29 Nov 2021

Souto Bernardino, Triunfante Vera, Santos-Pereira Ana, Martins Joana, Araújo Pedro M M, Osório Nuno S

Abstract excerpt

The extensive genetic diversity of HIV-1 is a major challenge for the prevention and treatment of HIV-1 infections. Subtype C accounts for most of the HIV-1 infections in the world but has been mainly localized in Southern Africa, Ethiopia and India. For elusive reasons, South Brazil harbors the largest HIV-1 subtype C epidemic in the American continent that is elsewhere dominated by subtype B. To investigate...

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Brazil
CD4-Positive T-Lymphocytes
Geography
HIV-1
HIV Infections
HIV Seropositivity

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Molecular Epidemiology

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PMID: 34845263
DOI: 10.1038/s41598-021-02428-3
PMCID: PMC8629974

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