VNTR polymorphism in the breakpoint region of ABL1 and susceptibility to bladder cancer.

Abstract excerpt

BACKGROUND: ABL1 is primarily known as a leukemia-related oncogene due to translocation, but about 2.2% of ABL1 mutations have been identified in bladder cancer, and high expression in solid cancer has also been detected. METHODS: Here, we used the NCBI database, UCSC genome browser gateway and Tandem repeat finder program to investigate the structural characterization of the ABL1 breakpoint region and to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aged
• Share to Alleles
• Share to Case-Control Studies