Article
Possible genetic influence on conjugate formation in salicylic acid metabolism.
Archives internationales de pharmacodynamie et de therapie - 1 Jan 2000
Emudianughe T S
Abstract excerpt
Subjects (7 males and 7 females) were dosed with salicylic acid (1 g) and hourly urinary samples were analyzed for its metabolites. The results obtained showed that the female subjects had higher capacity for salicylurate formation than the male (P less than or equal to 0.025). The urinary hourly excretion ratio of salicylurate and salicylglucuronic acid was about or greater than 1 while in the male this ratio is...
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