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Burkholderia cepacia Complex Regulation of Virulence Gene Expression: A Review

19 Jan 2017

Abstract excerpt

complex (Bcc) bacteria emerged as opportunistic pathogens in cystic fibrosis and immunocompromised patients. Their eradication is very difficult due to the high level of intrinsic resistance to clinically relevant antibiotics. Bcc bacteria have large and complex genomes, composed of two to four replicons, with variable numbers of insertion sequences. The complexity of Bcc genomes confers a high genomic plasticity...

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PMID: 28106859
DOI: 10.3390/genes8010043

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