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Article

Identification and functional analysis of a novel phospholipase D2 gene mutation associated with familial systemic lupus erythematosus.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 28 Mar 2021

Peng Lin, Yuan Xinke, Chen Lixiao, Chen Sijia, Chen Ke

Abstract excerpt

OBJECTIVES: Systemic lupus erythematosus (SLE) is a kind of autoimmune inflammatory connective tissue disease which seriously endangers human health. Genetic factors play a key role in the pathogenesis of SLE. This study aims to investigate a novel phospholipase D2 (PLD2) mutation associated with familial SLE, and further explore the underlying mechanism of the mutation in SLE. METHODS: The blood samples from a...

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Identifiers

PMID: 33927069
DOI: 10.11817/j.issn.1672-7347.2021.190589
PMCID: PMC10929931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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