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Gene Expression Profiling of Pancreas Neuroendocrine Tumors with Different Ki67-Based Grades

23 Apr 2021

Abstract excerpt

Pancreatic neuroendocrine tumors (PanNETs) display variable aggressive behavior. A major predictor of survival is tumor grade based on the Ki67 proliferation index. As information on transcriptomic profiles of PanNETs with different tumor grades is limited, we investigated 29 PanNETs (17 G1, 7 G2, 5 G3) for their expression profiles, mutations in 16 PanNET relevant genes and LINE-1 DNA methylation profiles. A...

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PMID: 33922803
DOI: 10.3390/cancers13092054

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