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Myelodysplasia Syndrome, Clonal Hematopoiesis and Cardiovascular Disease

19 Apr 2021

Abstract excerpt

The development of myelodysplasia syndromes (MDS) is multiphasic and can be driven by a plethora of genetic mutations and/or abnormalities. MDS is characterized by a hematopoietic differentiation block, evidenced by increased immature hematopoietic cells, termed blast cells and decreased mature circulating leukocytes in at least one lineage (i.e., cytopenia). Clonal hematopoiesis of indeterminate potential (CHIP)...

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PMID: 33921778
DOI: 10.3390/cancers13081968

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