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Cell-type-resolved quantitative proteomics map of interferon response against SARS-CoV-2

21 Apr 2021

Abstract excerpt

The commonly used laboratory cell lines are the first line of experimental models to study the pathogenicity and performing antiviral assays for emerging viruses. Here, we assessed the tropism and cytopathogenicity of the first Swedish isolate of SARS-CoV-2 in six different human cell lines, compared their growth characteristics, and performed quantitative proteomics for the susceptible cell lines. Overall,...

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PMID: 33898942
DOI: 10.1016/j.isci.2021.102420

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