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Peroxisome Proliferator-Activated Receptor Gamma Pro12Ala/C161T Genotypes and Risky Haplotype Altering Risk of Breast Cancer: A Turkish Case-Control Study.

Biochemical genetics - 1 Dec 2021

Unal Esra, Aslan Ezgi Irmak, Ozturk Tulin, Kurnaz Gomleksiz Ozlem, Kucukhuseyin Ozlem, Tuzuner M Bora, Seyhan M Fatih, Ozturk Oguz, Yilmaz Aydogan Hulya

Abstract excerpt

Breast cancer (BC) has a high incidence rate among women worldwide, and the mechanisms and etiology of this disease are not yet fully understood. The peroxisome proliferator-activated receptor gamma (PPARgamma), a nuclear hormone receptor that plays important roles in energy metabolism and cellular differentiation, is also suggested to be effective in cancer development. However, the results of studies...

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PMID: 33893920
DOI: 10.1007/s10528-021-10068-5

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