Article
Multimodal Imaging in a Patient With Alzheimer Disease and Parkinsonism Because of a Presenilin-1 Mutation.
Clinical nuclear medicine - 1 Sept 2021
Lu Jia-Ying, Sun Yi-Min, Yen Tzu-Chen, Zuo Chuan-Tao, Wang Jian
Abstract excerpt
ABSTRACT: A correct clinical diagnosis of motor dysfunction accompanied by cognitive impairment remains challenging. Recent advances in molecular imaging biomarkers hold promise to overcome this issue. A 37-year-old woman presenting with parkinsonism and cognitive impairment underwent both multimodal neuroimaging and genetic testing. Her main findings on PET included diffuse tau accumulation in the cerebral...
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