Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PET/MRI Delivers Multimodal Brain Signature in Alzheimer's Disease with De Novo PSEN1 Mutation.

Current Alzheimer research - 1 Jan 2021

Aghakhanyan Gayane, Saur Dorothee, Rullmann Michael, Weise Christopher M, Schroeter Matthias L, Marek Ken, Jamra Rami Abou, Tiepolt Solveig, Strauss Maria, Scherlach Cordula, Hoffmann Karl-Titus, Sabri Osama, Classen Joseph, Barthel Henryk

Abstract excerpt

BACKGROUND: Little is known so far about the brain phenotype and the spatial interplay of different Alzheimer's disease (AD) biomarkers with structural and functional brain connectivity in the early phase of autosomal-dominant AD (ADAD). Multimodal PET/MRI might be suitable to fill this gap. MATERIAL AND METHODS: We presented a 31-year-old male patient without a family history of dementia with progressive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Amyloid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Atrophy

Share to Magnetic Resonance Imaging

Share to Positron-Emission Tomography

Share to Presenilin-1

Share to tau Proteins

Source

Identifiers

PMID: 33855944
DOI: 10.2174/1567205018666210414111536

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PET/MRI Delivers Multimodal Brain Signature in Alzheimer's Disease with De Novo PSEN1 Mutation.PMID 33855944Read ↗

Multimodal PET/MR Imaging in Early-onset Alzheimer's Disease With Parkinsonism due to a Novel Presenilin-1 (M233I) Mutation.Semantic proximity Read ↗

Multimodal Imaging in a Patient With Alzheimer Disease and Parkinsonism Because of a Presenilin-1 Mutation.Semantic proximity Read ↗

Neuroimaging within the Dominantly Inherited Alzheimer’s Network (DIAN): PET and MRISemantic proximity Read ↗

MR, (18)F-FDG, and (18)F-AV45 PET correlate with AD PSEN1 original phenotype.Semantic proximity Read ↗

The Knight Alzheimer Research Imaging (KARI) dataset: a comprehensive multimodal resource for exploring aging, preclinical, and symptomatic Alzheimer disease pathologySemantic proximity Read ↗

Dissecting the Many Faces of Frontotemporal Dementia: An Imaging Perspective.Semantic proximity Read ↗

Progressive cognitive impairment and familial spastic paraparesis due to PRESENILIN 1 mutation: anatomoclinical characterization.Semantic proximity Read ↗

Case Report of a 47-Year-Old Long COVID Patient Diagnosed With Alzheimer's DiseaseSemantic proximity Read ↗

Clinical, biological, and imaging features of monogenic Alzheimer's Disease.Semantic proximity Read ↗

Multimodal Fusion Analysis of [18F]Florbetapir PET and Multiscale Functional Network Connectivity in Alzheimer’s DiseaseSemantic proximity Read ↗

Phenotypic profile of early-onset familial Alzheimer's disease caused by presenilin-1 E280A mutation.Semantic proximity Read ↗

Global dissection of the impact of Alzheimer’s disease on brain architecture and behavior: High resolution MRH resolves robust regional effectsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.