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Article

Designing of potent inhibitors for metallo-beta-lactamases producing Escherichia coli in molecular specification hereto.

Pakistan journal of pharmaceutical sciences - 1 Nov 2020

Rehman Noor, Azam Sadiq, Ali Amjad, Khan Ibrar, Asghar Muhammad, Waqas Muhammad, Ullah Farman, Zeb Zermina, Sehra Gul-E-, Absar Muhammad

Abstract excerpt

The rapid spread of Metallo-β-Lactamases producing Gram-negative bacteria in Pakistan is alarming and novel inhibitors with multi inhibition potential are required. In the current study, an effort was made to identify the resistance genes of MBLs producing E. coli and single inhibitor was designed having the potential to block all resistant proteins. Results showed that out of 573 clinical isolates, 14.1% MBLs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33879432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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