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Article

A Combination of Single Nucleotide Polymorphisms is Associated with the Interindividual Variability of Cholesterol Bioavailability in Healthy Adult Males.

Molecular nutrition & food research - 1 Nov 2020

Desmarchelier Charles, Wolff Estelle, Defoort Catherine, Nowicki Marion, Morange Pierre-Emmanuel, Alessi Marie-Christine, Valéro René, Nicolay Alain, Lairon Denis, Borel Patrick

Abstract excerpt

SCOPE: Cholesterol bioavailability displays a high interindividual variability, partly due to genetic factors. Existing studies have focused on single nucleotide polymorphisms (SNPs) analyzed individually, which only explained a minor fraction of the variability of this complex phenotype. The aim is to identify a combination of SNPs associated with a significant part of the variability in cholesterol...

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PMID: 32996248
DOI: 10.1002/mnfr.202000480

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