Article
3D-bioprinting ready-to-implant anisotropic menisci recapitulate healthy meniscus phenotype and prevent secondary joint degeneration.
Theranostics - 1 Jan 2021
Sun Ye, Zhang Yuxin, Wu Qiang, Gao Feng, Wei Yongzhong, Ma Yimin, Jiang Wenbo, Dai Kerong
Abstract excerpt
Objectives: Disruption of anisotropic phenotypes of the meniscus would contribute to OA progression. Exploring phenotype changes of the anisotropic meniscus in joint degeneration would help understand the biologic interaction between the meniscus and OA, and further facilitate the therapeutic strategies of meniscus injury-related joint degeneration. Meanwhile, engineering biomimetic meniscal tissue mimicking the...
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