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Article

Genetic Association of Interleukin 33/ST2 Polymorphisms With Behcet's Uveitis.

Frontiers in immunology - 1 Jan 2021

Pei Minghang, Liu Xinshu, Yang Peizeng, Zhao Chan, Gao Fei, Qu Yi, Liang Anyi, Xiao Junyan, Zhang Meifen

Abstract excerpt

Interleukin (IL)33, a member of the IL1 superfamily, functions as a nuclear factor and mediates biological effects by interacting with the ST2 receptor. Recent studies have described IL33 as an emerging pro-inflammatory cytokine in the immune system, and IL33/ST2 gene polymorphisms have been implicated in the pathogenesis of various immune diseases. However, the underlying mechanisms of IL33/ST2 in Behcet's...

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Identifiers

PMID: 33859633
DOI: 10.3389/fimmu.2021.589639
PMCID: PMC8043080

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