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Article

Novel pathogenic role for galectin-3 in early disease stages of arrhythmogenic cardiomyopathy.

Heart rhythm - 1 Aug 2021

Cason Marco, Celeghin Rudy, Marinas Maria Bueno, Beffagna Giorgia, Della Barbera Mila, Rizzo Stefania, Remme Carol Ann, Bezzina Connie R, Tiso Natascia, Bauce Barbara, Thiene Gaetano, Basso Cristina, Pilichou Kalliopi

Abstract excerpt

BACKGROUND: Arrhythmogenic cardiomyopathy (AC) is a myocardial disease due to desmosomal mutations whose pathogenesis is incompletely understood. OBJECTIVE: The purpose of this study was to identify molecular pathways underlying early AC by gene expression profiling in both humans and animal models. METHODS: RNA sequencing for differentially expressed genes (DEGs) was performed on the myocardium of transgenic...

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Share to Arrhythmogenic Right Ventricular Dysplasia
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33857645
DOI: 10.1016/j.hrthm.2021.04.006

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