Article
Influence of LGALS3 gene polymorphisms on susceptibility and prognosis of dilated cardiomyopathy in a Northern Han Chinese population.
Gene - 5 Feb 2018
Zhang Yuhui, Wang Yunhong, Zhai Mei, Gan Tianyi, Zhao Xuemei, Zhang Rongcheng, An Tao, Huang Yan, Zhou Qiong, Zhang Jian
Abstract excerpt
BACKGROUND: Galectin-3 plays an important role in modulating cardiac inflammation and fibrosis. It also takes part in the pathways underlying cardiac remodeling. Therefore, LGALS3 gene, encoding galectin-3 protein, is a promising candidate for the genetic study of dilated cardiomyopathy (DCM). To date, there has been no research evaluating the association between LGALS3 gene polymorphisms and the susceptibility...
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