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Article

BRD4: An emerging prospective therapeutic target in glioma

7 Mar 2021

Abstract excerpt

Despite advances in treatment, the prognosis for glioma patients remains poor. Bromodomain-containing protein 4 (BRD4), a member of the bromodomain and extraterminal (BET) protein family, plays an important role in controlling oncogene expression and genome stability. In recent years, numerous BRD4 inhibitors have entered clinical trials and achieved exciting results in tumor treatment. Recent clinical studies...

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PMID: 33851008
DOI: 10.1016/j.omto.2021.03.005

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