Article
STORM imaging reveals the spatial arrangement of transition zone components and IFT particles at the ciliary base in Tetrahymena.
Scientific reports - 12 Apr 2021
Hazime Khodor S, Zhou Zhu, Joachimiak Ewa, Bulgakova Natalia A, Wloga Dorota, Malicki Jarema J
Abstract excerpt
The base of the cilium comprising the transition zone (TZ) and transition fibers (TF) acts as a selecting gate to regulate the intraflagellar transport (IFT)-dependent trafficking of proteins to and from cilia. Before entering the ciliary compartment, IFT complexes and transported cargoes accumulate at or near the base of the cilium. The spatial organization of IFT proteins at the cilia base is key for...
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