Article
Inborn errors of STAT1 immunity.
Current opinion in immunology - 1 Oct 2021
Mizoguchi Yoko, Okada Satoshi
Abstract excerpt
Signal transducer and activator of transcription 1 (STAT1) is a latent cytoplasmic transcription factor that is activated by multiple stimuli, including type I, II, and III interferons and interleukin-27. Inborn errors of human STAT1 immunity underlie 4 distinct disorders: autosomal recessive (AR) complete STAT1 deficiency, AR partial STAT1 deficiency, autosomal dominant (AD) STAT1 deficiency, and AD STAT1...
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