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Article

Punctuated Loci on Chromosome IV Determine Natural Variation in Orsay Virus Susceptibility of Caenorhabditis elegans Strains Bristol N2 and Hawaiian CB4856.

Journal of virology - 24 May 2021

Sterken Mark G, van Sluijs Lisa, Wang Yiru A, Ritmahan Wannisa, Gultom Mitra L, Riksen Joost A G, Volkers Rita J M, Snoek L Basten, Pijlman Gorben P, Kammenga Jan E

Abstract excerpt

Host-pathogen interactions play a major role in evolutionary selection and shape natural genetic variation. The genetically distinct Caenorhabditis elegans strains, Bristol N2 and Hawaiian CB4856, are differentially susceptible to the Orsay virus (OrV). Here, we report the dissection of the genetic architecture of susceptibility to OrV infection. We compare OrV infection in the relatively resistant wild-type...

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Identifiers

PMID: 33827942
DOI: 10.1128/JVI.02430-20
PMCID: PMC8315983

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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