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Article

Plasma Cortisol and Risk of Atrial Fibrillation: A Mendelian Randomization Study.

The Journal of clinical endocrinology and metabolism - 16 Jun 2021

Larsson Susanna C, Lee Wei-Hsuan, Burgess Stephen, Allara Elias

Abstract excerpt

CONTEXT: Atrial fibrillation (AF), cardiac arrhythmias, and related risk factors are common in patients with Cushing's syndrome, or clinical chronic hypercortisolism. While hypercortisolism may be associated with AF, this association has not yet been ascertained causally. OBJECTIVE: To determine whether plasma cortisol is causally associated with AF using a 2-sample Mendelian randomization (MR) design. METHODS:...

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alpha 1-Antitrypsin
Atrial Fibrillation
Blood Pressure
Cushing Syndrome
Heart Disease Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Waist Circumference

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Identifiers

PMID: 33822969
DOI: 10.1210/clinem/dgab219
PMCID: PMC8208666

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