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KIFC1 regulates ZWINT to promote tumor progression and spheroid formation in colorectal cancer

5 Apr 2021

Abstract excerpt

Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide. Kinesin Family Member C1 (KIFC1) has been proposed as a promising therapeutic target due to its pivotal role in centrosome clustering to mediate cancer cell progression. This study aimed to analyze the expression and biological function of KIFC1 in CRC. Immunohistochemically, 67 (52%) of 129 CRC cases were positive for...

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PMID: 33819373
DOI: 10.1111/pin.13098

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