Bridging animal and clinical research during SARS-CoV-2 pandemic: A new-old challenge.

doi:10.1016/j.ebiom.2021.103291

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Article

Bridging animal and clinical research during SARS-CoV-2 pandemic: A new-old challenge.

EBioMedicine - 1 Apr 2021

Winkler Martin S, Skirecki Tomasz, Brunkhorst Frank M, Cajander Sara, Cavaillon Jean-Marc, Ferrer Ricard, Flohé Stefanie B, García-Salido Alberto, Giamarellos-Bourboulis Evangelos J, Girardis Massimo, Kox Matthijs, Lachmann Gunnar, Martin-Loeches Ignacio, Netea Mihai G, Spinetti Thibaud, Schefold Joerg C, Torres Antoni, Uhle Florian, Venet Fabienne, Weis Sebastian, Scherag André, Rubio Ignacio, Osuchowski Marcin F

Abstract excerpt

Many milestones in medical history rest on animal modeling of human diseases. The SARS-CoV-2 pandemic has evoked a tremendous investigative effort primarily centered on clinical studies. However, several animal SARS-CoV-2/COVID-19 models have been developed and pre-clinical findings aimed at supporting clinical evidence rapidly emerge. In this review, we characterize the existing animal models exposing their...

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Identifiers

PMID: 33813139
DOI: 10.1016/j.ebiom.2021.103291
PMCID: PMC8016444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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