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Article

Soluble Fraction from Lysate of a High Concentration Multi-Strain Probiotic Formulation Inhibits TGF-β1-Induced Intestinal Fibrosis on CCD-18Co Cells.

Nutrients - 9 Mar 2021

Lombardi Francesca, Augello Francesca Rosaria, Palumbo Paola, Mollsi Elona, Giuliani Maurizio, Cimini Anna Maria, Cifone Maria Grazia, Cinque Benedetta

Abstract excerpt

Fibrosis is a severe complication of chronic inflammatory disorders, such as inflammatory bowel disease (IBD). Current strategies are not fully effective in treating fibrosis; therefore, innovative anti-fibrotic approaches are urgently needed. TGF-β1 plays a central role in the fibrotic process by inducing myofibroblast differentiation and excessive extracellular matrix (ECM) protein deposition. Here, we explored...

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Identifiers

PMID: 33803197
DOI: 10.3390/nu13030882
PMCID: PMC7998462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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