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Article

A fifth human cytomegalovirus glycoprotein B genotype.

Research in virology - 1 Jan 2000

Shepp D H, Match M E, Lipson S M, Pergolizzi R G

Abstract excerpt

Genetic variation in glycoprotein B (gB) may play a role in human cytomegalovirus (HCMV) pathogenesis. Using restriction endonuclease digestion and DNA sequencing, a unique gB genotype was identified in eight HCMV strains isolated from five patients with the acquired immune deficiency syndrome. Nucleic acid homology to the four previously described gB genotypes ranged from 79 to 91% for the two major variable...

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PMID: 9602505
DOI: 10.1016/s0923-2516(98)80086-1

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