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Deep Learning Reveals Key Immunosuppression Genes and Distinct Immunotypes in Periodontitis

12 Mar 2021

Abstract excerpt

BACKGROUND: Periodontitis is a chronic immuno-inflammatory disease characterized by inflammatory destruction of tooth-supporting tissues. Its pathogenesis involves a dysregulated local host immune response that is ineffective in combating microbial challenges. An integrated investigation of genes involved in mediating immune response suppression in periodontitis, based on multiple studies, can reveal genes...

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PMID: 33777111
DOI: 10.3389/fgene.2021.648329

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