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Article

NK Cells in Autoimmune Diseases: Protective or Pathogenic?

Frontiers in immunology - 1 Jan 2021

Liu Meifang, Liang Shujuan, Zhang Cai

Abstract excerpt

Autoimmune diseases generally result from the loss of self-tolerance (i.e., failure of the immune system to distinguish self from non-self), and are characterized by autoantibody production and hyperactivation of T cells, which leads to damage of specific or multiple organs. Thus, autoimmune diseases can be classified as organ-specific or systemic. Genetic and environmental factors contribute to the development...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33777006
DOI: 10.3389/fimmu.2021.624687
PMCID: PMC7994264

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