Article
Generation of an induced pluripotent stem cell line SDUBMSi005-A from a patient with double primary gastric and colon carcinoma.
Stem cell research - 1 May 2021
Li Yan, Liu Xiaolin, Chen Dandan, Liu Yong, Ma Yanyan, Liu Qiji, Sun Wenjie, Li Jisheng
Abstract excerpt
It has been reported that mutations in CDH1 gene are associated with genetic susceptibility to colon, stomach, breast and prostate cancers. Here, an induced pluripotent stem cell (iPSC) line from a patient with double primary gastric and colon carcinoma carrying germline mutation (c. 1679C > G) in CDH1 gene was generated. The iPSC line had normal karyotype, expressed pluripotent markers and had ability to...
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