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Inflammatory Bowel Disease in Patients with Congenital Chloride Diarrhoea.

Journal of Crohn's & colitis - 7 Oct 2021

Norsa Lorenzo, Berni Canani Roberto, Duclaux-Loras Remi, Bequet Emeline, Köglmeier Jutta, Russell Richard K, Uhlig Holm H, Travis Simon, Hollis Jennifer, Koletzko Sibylle, Grimaldi Giusi, Castaldo Giuseppe, Rodrigues Astor, Deflandre Jaques, Dembinski Lukasz, Shah Neil, Heinz-Erian Peter, Janecke Andreas, Leskinen Saara, Wedenoja Satu, Koskela Ritva, Lachaux Alain, Kolho Kaija-Leena, Ruemmele Frank M

Abstract excerpt

BACKGROUND: Congenital chloride diarrhoea [CLD] is a rare autosomal recessive disease caused by mutations in the solute family carrier 26 member 3 [SLC26A3] gene. Patients suffer from life-long watery diarrhoea and chloride loss. Inflammatory bowel disease [IBD] has been reported in individual patients with CLD and in scl26a3-deficient mice. METHODS: We performed an international multicentre analysis to build a...

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Chloride-Bicarbonate Antiporters
Cohort Studies
Diarrhea
Europe

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Inflammatory Bowel Diseases

Metabolism, Inborn Errors

Sulfate Transporters

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PMID: 33770165
DOI: 10.1093/ecco-jcc/jjab056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Inflammatory Bowel Disease in Patients with Congenital Chloride Diarrhoea.PMID 33770165Read ↗

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