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Article

Long-term clinical outcome in patients with congenital chloride diarrhea.

Journal of pediatric gastroenterology and nutrition - 1 Apr 2006

Hihnala Satu, Höglund Pia, Lammi Laura, Kokkonen Jorma, Ormälä Timo, Holmberg Christer

Abstract excerpt

OBJECTIVES: Congenital chloride diarrhea (CLD) is a rare, autosomal recessive disorder of intestinal Cl/HCO3 exchange caused by mutations in the SLC26A3 gene and characterized by persistent Cl rich diarrhea from birth. Treatment is symptomatic and replacement therapy with NaCl and KCl has been shown to be effective in children, but the long-term prognosis remains unclear. We studied the largest known cohort of...

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Source

Identifiers

PMID: 16641574
DOI: 10.1097/01.mpg.0000214161.37574.9a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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