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Article

Changes in the Morphology, Number, and Protein Levels of Plasma Exosomes in CADASIL Patients.

Journal of Alzheimer's disease : JAD - 1 Jan 2021

Gao Dandan, Shang Junkui, Sun Ruihua, Shi Yingying, Jiang Haisong, Ma Mingming, Zhang Jiewen

Abstract excerpt

BACKGROUND: Exosomes are nano-sized extracellular vesicles which are secreted by cells and usually found in body fluids. Previous research has shown that exosomal secretion and autophagy-lysosomal pathway synergistically participates in intracellular abnormal protein elimination. The main pathological manifestations of Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy...

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PMID: 33749657
DOI: 10.3233/JAD-210101

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