Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combining bulk and single-cell RNA-sequencing data to reveal gene expression pattern of chondrocytes in the osteoarthritic knee

1 Jan 2021

Abstract excerpt

Osteoarthritis (OA) occurs mostly in the knees, hips, finger interphalangeal joints, and spinal facet joints, and is characterized by cartilage degeneration. The existing bulk RNA sequencing (bulk RNA-seq) and single-cell sequencing (scRNA-seq) data for chondrocytes in the osteoarthritic knee joint provide the expression profiles of entire cell populations and individual cells, respectively. Here, we aimed to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Extracellular vesicles in disease
Share to Osteoarthritis Treatment and Mechanisms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33749514
DOI: 10.1080/21655979.2021.1903207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combining bulk and single-cell RNA-sequencing data to reveal gene expression pattern of chondrocytes in the osteoarthritic kneePMID 33749514Read ↗

Single-cell RNA seq analysis identifies the biomarkers and differentiation of chondrocyte in human osteoarthritisSemantic proximity Read ↗

From cells to clinic: Single-cell transcriptomics shaping the future of orthopedicsSemantic proximity Read ↗

Identification of key biomarkers related to fibrocartilage chondrocytes for osteoarthritis based on bulk, single-cell transcriptomic dataSemantic proximity Read ↗

The Identification of Immune-Related Biomarkers for Osteoarthritis Immunotherapy Based on Single-Cell RNA Sequencing AnalysisSemantic proximity Read ↗

Integrated single-cell and bulk RNA sequencing analysis identified pyroptosis-related signature for diagnosis and prognosis in osteoarthritisSemantic proximity Read ↗

Single-cell RNA-seq analysis reveals the progression of human osteoarthritis.Semantic proximity Read ↗

A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritisSemantic proximity Read ↗

Identification of cellular heterogeneity and immunogenicity of chondrocytes via single-cell RNA sequencing technique in human osteoarthritisSemantic proximity Read ↗

Single‐cell <scp>RNA</scp> sequencing in osteoarthritisSemantic proximity Read ↗

Gene Expression Analysis of RNA-Seq Data from Human Osteoarthritis KneeSemantic proximity Read ↗

Whole-Transcriptome Sequence of Degenerative Meniscus Cells Unveiling Diagnostic Markers and Therapeutic Targets for OsteoarthritisSemantic proximity Read ↗

Single-Cell Profiles of Age-Related Osteoarthritis Uncover Underlying Heterogeneity Associated With Disease ProgressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.