Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unraveling the Molecular Nexus between GPCRs, ERS, and EMT

1 Jan 2021

Abstract excerpt

G protein‐coupled receptors (GPCRs) represent a large family of transmembrane proteins that transduce an external stimulus into a variety of cellular responses. They play a critical role in various pathological conditions in humans, including cancer, by regulating a number of key processes involved in tumor formation and progression. The epithelial‐mesenchymal transition (EMT) is a fundamental process in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Endoplasmic Reticulum Stress and Disease
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33746610
DOI: 10.1155/2021/6655417

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unraveling the Molecular Nexus between GPCRs, ERS, and EMTPMID 33746610Read ↗

The role of the unfolded protein response in cancer progression: From oncogenesis to chemoresistanceSemantic proximity Read ↗

An Insight into GPCR and G-Proteins as Cancer DriversSemantic proximity Read ↗

Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulumSemantic proximity Read ↗

Endoplasmic reticulum stress signaling and chemotherapy resistance in solid cancersSemantic proximity Read ↗

Endoplasmic Reticulum Stress and CancerSemantic proximity Read ↗

ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1/FoxO1 activationSemantic proximity Read ↗

The Role of the ER-Induced UPR Pathway and the Efficacy of Its Inhibitors and Inducers in the Inhibition of Tumor ProgressionSemantic proximity Read ↗

Targeting the hallmarks of cancer with therapy-induced endoplasmic reticulum (ER) stressSemantic proximity Read ↗

Dual role of Endoplasmic Reticulum Stress-Mediated Unfolded Protein Response Signaling Pathway in CarcinogenesisSemantic proximity Read ↗

Integrated Endoplasmic Reticulum Stress Responses in CancerSemantic proximity Read ↗

Impact of Obesity-Related Endoplasmic Reticulum Stress on Cancer and Associated Molecular TargetsSemantic proximity Read ↗

Illuminating the Onco-GPCRome: Novel G protein–coupled receptor-driven oncocrine networks and targets for cancer immunotherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.