Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic regulation of DAT gene promoter modulates the risk of externalizing and internalizing behaviors on a normative population: An explorative study.

Behavioural brain research - 21 May 2021

Carpentieri Valentina, Cerniglia Luca, Cimino Silvia, Pucci Mariangela, Pascale Esterina, D'Addario Claudio, Adriani Walter

Abstract excerpt

Accumulating research addressed epigenetic modifications and their role on behavioral phenotypes. We recently proposed to study methylation dynamics of two CpG motifs within the 5'-UTR of dopamine transporter (DAT) gene. Starting from a normative population sample of young adults, we selected three sub-groups based on their prevalent symptoms: subjects were assigned to Internalizing, Externalizing and Low-risk...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Behavioral Symptoms
Share to CpG Islands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Dopamine Plasma Membrane Transport Proteins

Share to Epigenesis, Genetic

Share to Promoter Regions, Genetic

Share to Young Adult

Source

Identifiers

PMID: 33745985
DOI: 10.1016/j.bbr.2021.113246

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic regulation of DAT gene promoter modulates the risk of externalizing and internalizing behaviors on a normative population: An explorative study.PMID 33745985Read ↗

DNA Methylation and Allelic Polymorphism at the Dopamine Transporter Promoter Affect Internalizing and Externalizing Symptoms in Preschoolers.Semantic proximity Read ↗

Methylation patterns within 5'-UTR of DAT1 gene as a function of allelic 3'-UTR variants and their maternal or paternal origin: May these affect the psychopathological phenotypes in children? An explorative study.Semantic proximity Read ↗

DNA Methylation at the DAT Promoter and Risk for Psychopathology: Intergenerational Transmission between School-Age Youths and Their Parents in a Community SampleSemantic proximity Read ↗

Involvement of DAT1 Gene on Internet Addiction: Cross-Correlations of Methylation Levels in 5'-UTR and 3'-UTR Genotypes, Interact with Impulsivity and Attachment-Driven Quality of Relationships.Semantic proximity Read ↗

Epigenome-wide DNA methylation in externalizing behaviours: A review and combined analysisSemantic proximity Read ↗

Dopamine transporter polymorphism associated with externalizing behavior problems in children.Semantic proximity Read ↗

Genomic features of the human dopamine transporter gene and its potential epigenetic States: implications for phenotypic diversity.Semantic proximity Read ↗

A longitudinal study of epigenetic variation in twins.Semantic proximity Read ↗

Global DNA methylation changes in adults with attention deficit-hyperactivity disorder and its comorbidity with bipolar disorder: links with polygenic scoresSemantic proximity Read ↗

Epigenetic Analysis of the Dopamine Transporter Gene DAT1 with a Focus on Personality Traits in Athletes.Semantic proximity Read ↗

Verbal but not performance IQ is highly correlated to externalizing behavior in boys with ADHD carrying both DRD4 and DAT1 risk genotypes.Semantic proximity Read ↗

Potential for diagnosis versus therapy monitoring of attention deficit hyperactivity disorder: a new epigenetic biomarker interacting with both genotype and auto-immunity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.