Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Verbal but not performance IQ is highly correlated to externalizing behavior in boys with ADHD carrying both DRD4 and DAT1 risk genotypes.

Progress in neuro-psychopharmacology & biological psychiatry - 31 Aug 2009

Kebir Oussama, Grizenko Natalie, Sengupta Sarojini, Joober Ridha

Abstract excerpt

OBJECTIVE: Attention-deficit/hyperactivity disorder (ADHD) is often associated with reduced IQ and high levels of externalizing behavior (EB). This study tested if DRD4 7-repeat allele and DAT1 10-repeat allele homozygosity interact in modulating correlations between IQ and EB in affected boys. METHODS: Boys (n=130) between 6 and 12 years of age diagnosed with ADHD were included in the study. IQ and EB were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Intelligence
Share to Attention Deficit Disorder with Hyperactivity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dopamine Plasma Membrane Transport Proteins

Share to Heterozygote

Share to Intelligence Tests

Share to Receptors, Dopamine D4

Share to Social Behavior

Share to Verbal Behavior

Source

Identifiers

PMID: 19409950
DOI: 10.1016/j.pnpbp.2009.04.019

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Verbal but not performance IQ is highly correlated to externalizing behavior in boys with ADHD carrying both DRD4 and DAT1 risk genotypes.PMID 19409950Read ↗

The dopamine D4 receptor gene and moderation of the association between externalizing behavior and IQ.Semantic proximity Read ↗

ADHD: relation between cognitive characteristics and DAT1 / DRD4 dopamine polymorphismsSemantic proximity Read ↗

DNA Methylation and Allelic Polymorphism at the Dopamine Transporter Promoter Affect Internalizing and Externalizing Symptoms in Preschoolers.Semantic proximity Read ↗

[Effects of the D4 dopamine receptor gene variation on behavior problems at 6 years of age].Semantic proximity Read ↗

Intelligence in DSM-IV combined type attention-deficit/hyperactivity disorder is not predicted by either dopamine receptor/transporter genes or other previously identified risk alleles for attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

Prediction of Heterogeneity in Intelligence and Adult Prognosis by Genetic Polymorphisms in the Dopamine System Among Children With Attention-Deficit/Hyperactivity DisorderSemantic proximity Read ↗

Neuropsychological performance measures as intermediate phenotypes for attention-deficit/hyperactivity disorder: A multiple mediation analysis.Semantic proximity Read ↗

An examination of the behavioral and neuropsychological correlates of three ADHD candidate gene polymorphisms (DRD4 7+, DBH TaqI A2, and DAT1 40 bp VNTR) in hyperactive and normal children followed to adulthood.Semantic proximity Read ↗

Understanding genes, environment and their interaction in attention-deficit hyperactivity disorder: is there a role for neuroimaging?Semantic proximity Read ↗

Testing DAT1 and DRD4 Genes in Attention Deficit Hyperactivity Disorder Using a Wide Spectrum of Neurocognitive Batteries.Semantic proximity Read ↗

Decreasing ADHD phenotypic heterogeneity: searching for neurobiological underpinnings of the restrictive inattentive phenotype.Semantic proximity Read ↗

Attention-deficit hyperactivity disorder: a study of association with both the dopamine transporter gene and the dopamine D4 receptor gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.