Article
Race disparities in genetic alterations within Wilms tumor specimens.
Journal of pediatric surgery - 1 Jun 2021
Apple Annie N, Neuzil Kevin E, Phelps Hannah M, Li Bingshan, Lovvorn Iii Harold N
Abstract excerpt
BACKGROUND: Wilms tumor (WT) affects Black children disproportionately. Genetic aberrations within WT specimens that contribute to this disparity have not been reported. METHODS: The Therapeutically Applied Research to Generate Effective Treatments (TARGET) database was queried for WT patient and genomic features. Clinical and genetic variables were compared by race. RESULTS: Within the discovery set (enriched...
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