Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variants c.677 C>T, c.1298 A>C in MTHFR, and c.66 A>G in MTRR Affect the Occurrence of Recurrent Pregnancy Loss in Chinese Women.

Genetic testing and molecular biomarkers - 1 Nov 2020

Zhang Yan, Zhan Wenli, Du Qianyi, Wu Li, Ding Hongke, Liu Fenghua, Yin Aihua

Abstract excerpt

Objective: Although genetic variants of key enzymes in the folic acid-methionine metabolic circulation, including methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) were thought to be related to the risk of recurrent pregnancy loss (RPL), the results of recent studies have been inconsistent. Therefore, the present retrospective case-control study was designed to explore whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abortion, Habitual
Share to Abortion, Spontaneous

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to Ferredoxin-NADP Reductase

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Odds Ratio

Share to Pregnancy

Source

Open in PubMed Open full text

Identifiers

PMID: 33121283
DOI: 10.1089/gtmb.2020.0106
PMCID: PMC7698989

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variants c.677 C>T, c.1298 A>C in MTHFR, and c.66 A>G in MTRR Affect the Occurrence of Recurrent Pregnancy Loss in Chinese Women.PMID 33121283Read ↗

Association between maternal, fetal and paternal MTHFR gene C677T and A1298C polymorphisms and risk of recurrent pregnancy loss: a comprehensive evaluation.Semantic proximity Read ↗

The association between methionine synthase reductase c.66A>G variant and the risk of recurrent pregnancy loss: A systematic review and meta-analysis.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphisms and recurrent pregnancy loss in China: a systematic review and meta-analysis.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene A1298C polymorphism and susceptibility to recurrent pregnancy loss: a meta-analysis.Semantic proximity Read ↗

Maternal folate, alcohol and energy metabolism-related gene polymorphisms and the risk of recurrent pregnancy loss.Semantic proximity Read ↗

Association of MTR and MTRR polymorphisms with recurrent pregnancy loss: a case control study.Semantic proximity Read ↗

Association of Methylenetetrahydrofolate Reductase C677T and A1298C Gene Polymorphisms With Recurrent Pregnancy Loss in Syrian Women.Semantic proximity Read ↗

The association between 5, 10 - methylenetetrahydrofolate reductase and the risk of unexplained recurrent pregnancy loss in China: A Meta-analysis.Semantic proximity Read ↗

Correlation of methylation status in MTHFR promoter region with recurrent pregnancy lossSemantic proximity Read ↗

Association study between methylenetetrahydrofolate reductase polymorphisms and unexplained recurrent pregnancy loss: a meta-analysis.Semantic proximity Read ↗

MTHFR 1298A>C Substitution is a Strong Candidate for Analysis in Recurrent Pregnancy Loss: Evidence from 14,289 Subjects.Semantic proximity Read ↗

MTHFR C677T polymorphism and recurrent early pregnancy loss risk in north Indian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.