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Article

Spinal intramedullary H3K27M mutant glioma with vertebral metastasis: a case report.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Dec 2021

Handis Chafik, Tanrıkulu Bahattin, Danyeli Ayça Erşen, Özek M Memet

Abstract excerpt

A new entity of gliomas, named "diffuse midline glioma (DMG), H3K27M mutant (grade IV)," which represents a specific molecular profile, was introduced to the World Health Organization (WHO) classification 2016 of central nervous system tumors. Many midline localizations have been described for this glioma, and mainly the hypothalamus, pons, thalamus, and spinal cord are sites of predilection in pediatric and...

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PMID: 33742289
DOI: 10.1007/s00381-021-05119-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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