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ALK -rearranged Renal Cell Carcinoma (RCC): A Report of 2 Cases and Review of the Literature Emphasizing the Distinction Between VCL-ALK and Non- VCL-ALK RCC

17 Mar 2021

Abstract excerpt

Anaplastic lymphoma kinase (ALK) rearrangement-associated renal cell carcinoma ( ALK -rearranged RCC) is a new provisional entity that has been included in the 2016 World Health Organization classification of RCCs. We report 2 cases of ALK -rearranged RCC, 1 with a vinculin-ALK ( VCL-ALK ) fusion and the other with an EML4-ALK fusion. The VCL-ALK RCC occurred in a 14-year-old girl with sickle cell trait and...

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PMID: 33729862
DOI: 10.1177/10668969211003660

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