Article
Functional Study of Polymorphism 1888 C>T in the Promoter Region of Human PLUNC Gene.
The American journal of the medical sciences - 1 Mar 2021
Liu Beina, Wang Rong, He Ying
Abstract excerpt
BACKGROUND: Our previous study showed that a single nucleotide polymorphisms (SNP) of 1888 C>T located at promoter region of human PLUNC gene might affect the susceptibility of nasopharyngeal carcinoma (NPC) in a Chinese population. This study aims to analyze the effect of the genetic variant on PLUNC promoter activity. MATERIALS AND METHODS: The DNA fragments of the PLUNC promoter region including the SNP 1888...
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