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Article

Common and Rare Variants Genetic Association Analysis of Circulating Neutrophil Extracellular Traps.

Frontiers in immunology - 1 Jan 2021

Donkel Samantha J, Portilla Fernández Eliana, Ahmad Shahzad, Rivadeneira Fernando, van Rooij Frank J A, Ikram M Arfan, Leebeek Frank W G, de Maat Moniek P M, Ghanbari Mohsen

Abstract excerpt

Introduction: Neutrophils contribute to host defense through different mechanisms, including the formation of neutrophil extracellular traps (NETs). The genetic background and underlying mechanisms contributing to NET formation remain unclear. Materials and Methods: We performed a genome-wide association study (GWAS) and exome-sequencing analysis to identify common and rare genetic variants associated with plasma...

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Identifiers

PMID: 33717105
DOI: 10.3389/fimmu.2021.615527
PMCID: PMC7944992

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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