Article
Selection into shift work is influenced by educational attainment and body mass index: a Mendelian randomization study in the UK Biobank.
International journal of epidemiology - 30 Aug 2021
Daghlas Iyas, Richmond Rebecca C, Lane Jacqueline M, Dashti Hassan S, Ollila Hanna M, Schernhammer Eva S, Smith George Davey, Rutter Martin K, Saxena Richa, Vetter Céline
Abstract excerpt
BACKGROUND: Shift work is associated with increased cardiometabolic disease risk. This observation may be partly explained by cardiometabolic risk factors having a role in the selection of individuals into or out of shift work. We performed Mendelian randomization (MR) analyses in the UK Biobank (UKB) to test this hypothesis. METHODS: We used genetic risk scores (GRS) to proxy nine cardiometabolic risk factors...
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