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Clinical Utility of Targeted Next-Generation Sequencing in the Evaluation of Low-Grade Lymphoproliferative Disorders.

American journal of clinical pathology - 4 Aug 2021

Jajosky Audrey N, Havens Nathaniel P, Sadri Navid, Oduro Kwadwo A, Moore Erika M, Beck Rose C, Meyerson Howard J

Abstract excerpt

OBJECTIVES: We investigated the usefulness of a custom-designed 31-gene next-generation sequencing (NGS) panel implemented on a routine basis for the evaluation of low-grade lymphoproliferative disorders (LPDs). METHODS: In total, 147 blood, bone marrow, and tissue specimens were sequenced, including 81% B-cell, 15% T-cell, and 3% natural killer (NK)-cell neoplasms. RESULTS: Of the cases, 92 (63%) of 147...

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B-Lymphocytes
Bone Marrow
Killer Cells, Natural
Leukemia, Hairy Cell
Leukemia, Large Granular Lymphocytic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphoma, B-Cell

Lymphoproliferative Disorders

Waldenstrom Macroglobulinemia

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PMID: 33712839
DOI: 10.1093/ajcp/aqaa255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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