IDO2 rs10109853 polymorphism affects the susceptibility to multiple myeloma.

doi:10.1007/s10238-020-00681-w

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IDO2 rs10109853 polymorphism affects the susceptibility to multiple myeloma.

Clinical and experimental medicine - 1 May 2021

Kasamatsu Tetsuhiro, Hashimoto Nao, Sakaya Nao, Awata-Shiraiwa Maaya, Ishihara Rei, Murakami Yuki, Masuda Yuta, Gotoh Nanami, Nagai Kazue, Oda Tsukasa, Yokohama Akihiko, Saitoh Takayuki, Handa Hiroshi, Tsukamoto Norifumi, Hayashi Kunihiko, Murakami Hirokazu

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) of the IDO1 and IDO2 genes have been associated with some diseases. Here, we investigated the association of IDO1 and IDO2 SNPs with the susceptibility to multiple myeloma (MM) and their relationships with MM clinical features. We obtained genomic DNA from 100 patients with MM and 149 healthy race-matched controls and determined IDO1 promoter - 1849G/T (rs3824259) and IDO2...

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PMID: 33709342
DOI: 10.1007/s10238-020-00681-w

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