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Article

Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic cancer - 1 May 2021

Asselta Rosanna, Di Tommaso Luca, Perrino Matteo, Destro Annarita, Giordano Laura, Cardamone Giulia, Rubino Luca, Santoro Armando, Duga Stefano, Zucali Paolo Andrea

Abstract excerpt

BACKGROUND: Significant efforts have been made to investigate the molecular pathways involved in thymic carcinogenesis. However, genetic findings have still not impacted clinical practice. The aim of this exploratory trial was to evaluate the immunoscore and molecular profile of a series of thymic carcinomas (TCs), correlating this data with clinical outcome. METHODS: Formalin-fixed, paraffin-embedded (FFPE) TC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33704917
DOI: 10.1111/1759-7714.13765
PMCID: PMC8088947

Genes

CDKN2A
FGFR3

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