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Article

Profiles of mutations in hepatitis B virus surface and polymerase genes isolated from treatment-naïve Nigerians infected with genotype E.

Journal of medical microbiology - 1 Mar 2021

Olusola Babatunde A, Faneye Adedayo O, Oluwasemowo Olukunle O, Motayo Babatunde O, Adebayo Sopeju, Oludiran-Ayoade Ayomide E, Aleru Bisola, George Uwem E, Oragwa Arthur O

Abstract excerpt

Introduction. Hepatitis B virus (HBV) infection is the leading cause of hepatitis, liver cirrhosis, and hepatocellular carcinoma (HCC). HBV genotype E (HBV/E) is the predominant genotype in West Africa and has been linked epidemiologically with chronic and occult HBV infections as well as development of HCC. Mutations in the surface and polymerase genes of HBV have been associated with occult infection, drug...

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PMID: 33704041
DOI: 10.1099/jmm.0.001338

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