Molecular Epidemiology, Drug-Resistant Variants, and Therapeutic Implications of Hepatitis B Virus and Hepatitis D Virus Prevalence in Nigeria: A National Study.

doi:10.3390/pathogens14010101

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Molecular Epidemiology, Drug-Resistant Variants, and Therapeutic Implications of Hepatitis B Virus and Hepatitis D Virus Prevalence in Nigeria: A National Study.

Pathogens (Basel, Switzerland) - 20 Jan 2025

Adewuyi Oludare 'Sunbo, Balogun Muhammad Shakir, Otomaru Hirono, Abimiku Alash'le, Ahumibe Anthony Agbakizu, Ilori Elsie, Luong Que Anh, Mba Nwando, Avong James Christopher, Olaide John, Okunromade Oyeladun, Ahmad Adama, Akinpelu Afolabi, Ochu Chinwe Lucia, Olajumoke Babatunde, Abe Haruka, Ihekweazu Chikwe, Ifedayo Adetifa, Toizumi Michiko, Moriuchi Hiroyuki, Yanagihara Katsunori, Idris Jide, Yoshida Lay-Myint

Abstract excerpt

Information on circulating HBV (sub-)genotype, variants, and hepatitis D virus (HDV) coinfection, which vary by geographical area, is crucial for the efficient control and management of HBV. We investigated the genomic characteristics of HBV (with a prevalence of 8.1%) and the prevalence of HDV in Nigeria. We utilised 777 HBV-positive samples and epidemiological data from the two-stage sampled population-based,...

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PMID: 39861062
DOI: 10.3390/pathogens14010101
PMCID: PMC11768191

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