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Article

Virulence of "white-gray-opaque" tri-stable transformation in clinical Candida albicans in vitro and in vivo.

Microbial pathogenesis - 1 May 2021

Yang Jing, Feng Wenli, Xi Zhiqin, Yang Lu, Zhao Xiaoxia, Ma Yan, Ma Yanping

Abstract excerpt

The study aimed to induce the white-opaque-gray tri-stable transformation in clinical C. albicans and to explore their potential pathogenicity. Sixty-four clinical strains were used to induce the white, opaque and gray cells of C. albicans. Secreted aspartyl proteinases (Sap) activity of the three phenotypes was then measured, and a vulvovaginal candidiasis (VVC) animal model was constructed. Of the 64 clinical...

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Identifiers

PMID: 33689812
DOI: 10.1016/j.micpath.2021.104825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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